… (PT) injections allow high concentrations of therapeutic … promote retention of free or
encapsulated drugs at the tumor … thermoresponsive polymers, poloxamer-based hydrogels are …

… and into the systemic circulation via the high-pressure flow in the … chemotherapeutics into
poloxamer-based hydrogels is therefore … core, which helps to encapsulate hydrophobic drugs. …

… Poloxamer 407, a thermosensitive polymer that is a liquid at low temperatures but gels at
higher … Additionally, poloxamer 407 has been studied for use in a vehicle for local injection of a …

… ], etoposide [26] and doxorubicin [27], due to the high solubility of … entrapment efficiency for
various lipophilic drugs and ensure … Different poloxamer based in situ gels were prepared and …

… indicated preference for the traditional injection [1]. Other … it in a mucoadhesive and
thermosensitive hydrogel which was … Tetracaine quantification during the encapsulation efficiency …

… thermosensitive properties of poloxamer 338. Also released amount of DEX were decreased
due to the use of high … vitro drug release profiles of poloxamer based formulations were fit to …

… and an intramuscular depot injection. These preparations suffer … using high-performance
liquid chromatography (HPLC). … order release; in contrast, etoposide gels have been reported to …

… A few examples of these approaches are hydrogel based … -scale manufacturing, high
entrapment efficiency of both hydrophilic … index and of the optimized etoposide-loaded SLNs were …

… drug loading (DL) and encapsulation efficiency (EE) of the … The highest injection forces
were found for the 29G needles. … the injectable hydrogels was infected in the injection process […

… size distribution, zeta potential entrapment efficiency and ex vivo … The injected volume was
20 μL and detections were … nm where Poloxamer-based formulae possessed the lowest and …